Detecting intra-QRS ischemic changes in the ECG

Table of Contents

Coronary Ischemia Detecting intra-QRS changes in the ECG

Significance of ischemia detection

Possible manifestations of Ischemia in the ECG

The Continuous Wavelet Transform - properties

Detecting Detecting intra-QRS Ischemic Changes in the ECG 

Time domain ECG signal before PTCA (85% occlusion)

Time-frequency distribution (3D) of the QRS complex before PTCA (85% occlusion)

Time-frequency distribution (topo plot) of the QRS complex before PTCA (85% occlusion)

Time domain ECG signal during PTCA (after 20 min of inflation) 

Time-frequency distribution (3D) of the QRS complex during PTCA (after 20 min of inflation)

Time-frequency distribution (topo plot) of the QRS complex during PTCA (after 20 min of inflation) 

Time domain ECG signal during PTCA (after 10 min of reperfusion) 

Time-frequency distribution (3D) of the QRS complex during PTCA (after 10 min of reperfusion)

Time-frequency distribution (topo plot) of the QRS complex during PTCA (after 10 min of reperfusion) 

Related publications

1. Nitish V. Thakor, Boris Gramatikov and David Sherman. Wavelet (Time-Scale) Analysis in Biomedical Signal Processing. In The Biomedical Engineering Handbook, Ed. Joseph Bronzino, 2nd Edition., Volume I, Section VI (Biomedical Signal Analysis), Chapter 56, pp. 56.1 - 56.27. CRC Press LLC, IEEE Press, December 1999.

2. Gramatikov, B., Brinker, J., Yi-chun, S., Thakor, N. Wavelet analysis and time-frequency distributions of the Body Surface ECG before and after angioplasty.   Computer Methods and Programs in Biomedicine.  Vol. 62, No.2, June 2000, pp.87-98.

3. Shenai M., Gramatikov, B.I., Thakor, N.V. Computer models of depolarization alterations Induced by myocardial ischemia. The effect of superimposed ischemic inhomogeneities on propagation in space and time-frequency domains.  Journal of Biological Systems, Vol. 7, No.4, 1999,  pp. 553-574.

4. Gramatikov, B., Yi-chun, S., Rix, H., Caminal, P., Thakor, N.  Multiresolution wavelet analysis of the body surface ECG before and after angioplasty. Annals of Biomedical Engineering, Vol. 23, 1995, pp. 553-561.

5. Gramatikov, B. Iyer, V.  Ischemia-Related Depolarization Changes Detected in Body-Surface Ambulatory ECG Recordings.   Chicago 2000 World Congress on Medical Physics and Biomedical Engineering, July 23-28, 2000. Short paper. In Congress 2000 Proceedings on CD-ROM.

6. Shenai, M., Gramatikov, B., Thakor, N.V. Computer modeling of depolarization changes induced by myocardial ischemia. Computers in Cardiology 1998, Vol. 25, Cleveland, Ohio, Sept.13-16, 1998. pp. 321-324.

7. Gramatikov, B.I., Provaznik, I., Thakor, N.V. Depolarization Changes During Ischemia Detected Through Time-Frequency Analysis of the Intracardiac Electrogram. Computers in Cardiology 1998, Vol. 25, Cleveland, Ohio, Sept.13-16, 1998, pp. 289-292.

8. Gramatikov, B., Detschew, V., Grieszbach, G. Dynamische Spektralanalyse des EKG zur fruehzeitigen Erkennung von Myokardischaemie (Dynamic spectral analysis of the ECG for early detection of myocardial ischaemia). 39th International Colloquium of the Technical University Ilmenau, Sept.27-30, 1994, Ilmenau, Germany. In Proceedings, B-2.2.2., Vol.2, pp. 384-388.

9. Thakor, N., Yi-chun, S., Gramatikov, B., Rix, H., Caminal, P. Multiresolution wavelet analysis of ECG: Detection of ischemia and reperfusion in angioplasty. World Congress on Medical Physics and Biomedical Engineering, Rio de Janeiro, Brazil, August 1994, In Proceedings: RT15-2.4, p.392

10. Gramatikov, B, Thakor, N. Wavelet analysis of coronary artery occlusion related changes in ECG. 15th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 28-31, 1993, San Diego, California, USA. In Proceedings, p.731.

11. Thakor, N., Gramatikov, B., Mita, M. Multiresolution Wavelet Analysis of ECG during ischemia and reperfusion. Computers in Cardiology, London, 5-8 Sept. 1993. In Proceedings (IEEE Comp.Soc.Press), pp.895-898.